Tamoxifen Citrate | Nolvadex
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Trade Names: Tamoxifen, Nolvadex, Tamoximed, Valodex, Tamoplex.
Medical purpose: Therapy of estrogen-dependent breast cancer in women.
Use in sports: Post-cycle therapy, stopping the development of gynecomastia associated with a high level of estrogen.
Tamoxifen is an antiestrogen. Unlike aromatase inhibitors, it replaces estrogen in receptors. Mostly, it works like estrogen. There is a certain contradiction here, we can notice with you that in the action of Tamoxifen there are some factors that may contradict each other. The second point which should be understood is that with an excess of Tamoxifen in the body, we can really observe an increase in estradiol levels in the analyzes. It will inevitably manifest itself, it really is.
The substance is actively used in sports and quite often, not quite right.
What is not recommended to do:
- Apply Tamoxifen to reduce the level of estradiol in the blood.
- Apply Tamoxifen solo to increase testosterone levels (there are safer and more logical ways).
- Use substance on course (typical mistake).
In fact, the use of Tamoxifen solo in dosages of at least 20 mg per day, it is capable of long-term use of 3 weeks in the body in which the hormonal balance is not disturbed by anabolic steroids, this application can completely unbalance the level of the hormonal system. Moreover, according to the analysis, the level of estradiol may even increase. Because replacing estrogen in the receptors, everything that will accumulate from above will already circulate in the blood. Indeed, mild inhibition of testosterone levels and a slight increase in estradiol levels can be observed in the analyses. Therefore, the use of Solo, it requires in any case-control. If you think that you can get off in some easy ways without doing tests, without having to take anabolic steroids, but just sit on such a drug as Tamoxifen, this is not a very good prospect, because the tests must be done anyway, and testosterone levels have every chance of being suppressed.
Why did we use Tamoxifen initially? What is its starting use? Why it was invented?
And it was initially invented for contraception purposes in women. But after certain tests, circumstances, it can bind to receptors in breast cancer cells and thus prevent this same breast cancer, or prevent from developing it further. In the initial stages, it was observed how Tamoxifen could work as a prophylactic drug of preventing this cancer. Such an effect was really in demand, indeed the product came into wide production, received a patent for 40 years, in 2002 it ended, after which the so-called Generic analogs have already begun to be produced. But we are interested in it as a means of application in sports. It was noticed back in the golden era of bodybuilding when they began to use these drugs to adjust hormone levels.
In sports, as you know, we use Tamoxifen to ensure the right way out of the steroid cycle. Either exit from the cycle or go through on it completely on PCT, to normalize the level of hormones in the body and restore it to its circles as quickly as possible, minimizing the so-called rollback. It would be worth telling the difference between Tamoxifen and Clomid. I personally am inclined to the fact that Tamoxifen is a more optimal drug for Post Course Therapy. And the fact that Clomid is used everywhere and always, that’s why the majority is somehow stereotyped into the head, even though it has certain disadvantages.
The main advantages of Tamoxifen
- the recovery rate of FSH and LH is quite high at dosages of up to 40 mg
- binds to receptors throughout the body (unlike Clomid) except for bones
- active effect on gynecomastia with the ability to eliminate its initial signs for a period of 5 to 20 days
- due to active work in the liver, it has a positive effect on the level of LDL (bad cholesterol), reducing it
The main advantage of this drug at the initial stage is to remove the signs of gynecomastia. If itching in the nipples begins to appear, the areola on the nipple begins to increase, some unpleasant sensations that start pulling pain begin, general flooding, mood changes. That is, all the signs of aromatization with the prospect of gynecomastia, Tamoxifen can easily correct this situation. He really together with Anastrozole is able to smooth out this situation. But if you have these manifestations do not go on for six months. About this time is needed so that the connective tissue ceases to show any signs of inflammation and is already formed, the separate element that you can’t influence medically.
The main disadvantages of Tamoxifen
- individual tolerance;
- metabolic disorders, nausea, headache, dry lips and a short-term blurred vision;
- increase in AST and ALT;
- increased platelet count;
- violation of blood circulation in small vessels;
- severe depression;
- decreased libido;
- heart rhythm disturbance.
Tamoxifen is not recommended for use on the course since it completely inhibits any accumulative force from estradiol. And estradiol for muscle mass is simply needed. Here he has both advantages and disadvantages. From the point of view of eliminating gynecomastia, a dosage of 60 mg for 10 days can locally remove gynecomastia, but cause fluid retention and depress mood. Because Tamoxifen acts in the tissues of the mammary gland, in the one that you are trying to grow as intense as possible while suppressing it. But in such dosages, in all individual tissues in some of them, it acts as a full-fledged estrogen, thereby causing an increase in the level of estradiol in the blood. This is seen.
Regarding the side effects, Tamoxifen does not have the whole spectrum that is attributed to it as a rule, but it can cause those side effects that the same Clomid cannot cause. For example, from Tamoxifen, a situation is often observed when vision can be defocused. In particular, if you take it at night and take it to create the conditions of PCT, it is necessary at night. In the morning, the phenomenon of defocusing of vision may be observed and dry lips may be observed. That is, it dries to some extent the mucous membrane. In terms of libido, Tamoxifen can even increase libido by PCT in the first 5 to 6 days of taking in a dosage of 20 mg. And in the future, he can oppress him since there is a complete defocusing of the hormonal balance. In this case, Tamoxifen is not very useful and many people notice that in the second week of PCT conducted on Tamoxifen there is a very uninteresting libido, although there is a morning erection, and there is absolutely no desire.
In terms of thrombosis. Yes, it does increase both platelet count and general condition. It can slightly increase blood pressure, can increase the heart rate, can cause thirst, dryness, and at the same time increase the level of platelets. Acting directly on the blood. But this is usually observed in dosages of 40 mg. In this way, Tamoxifen has certain side effects, but they are most clearly manifested from large dosages. For example, at the stage of getting rid of gynecomastia in dosages of 60 mg, then they will manifest themselves much brighter.
What Post Therapy Therapy May Look Like.
- Tamoxifen 20 mg (1 tablet 20 mg at night)
4 – 10 day:
- Tamoxifen 40 mg (2 tablets at night)
Pass tests: FSH, LH, estradiol, free testosterone
12 – 22 day:
- Tamoxifen 10 mg (half a tablet at night)
Tamoxifen is taken with the calculation of the half-life of those steroids that you had, so you choose the starting date for taking it yourself.
As example I took Testosterone Propionate + Stanozolol cycle. As soon as we finish the course, we start Tamoxifen at 20 mg, only for that purpose so that the first 3 days we can check the reaction to it. Because no one canceled the individual reaction. The components of the drug can cause those effects that you will not like much, as can be a personal intolerance to some elements of the substance.
As soon as FSH and LH return to normal, estradiol drops from its very high values to values saner, testosterone leaves from zero or enters into abstract values due to the background work of the drug, Tamoxifen is canceled and further PCT passes on stimulants, on zinc, on yohimbine, etc.
That’s we briefly reviewed a drug like Tamoxifen. If you have any questions, write to us at firstname.lastname@example.org
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