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Testosterona C Balkan Pharma 1amp [200mg/ml]

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Balkan Testosterone

Commercial name

Testosterone C

 

The DCI of the active substance

Testosterone

 

Composite:

1 ml solution contains:

active substance: Testosterone Cypionate 200 mg;

excipients: benzyl alcohol, benzyl benzoate, peach oil.

 

Pharmaceutical form

Injectable solution

 

Description of the drug

Oily, transparent solution, from light-yellow to yellow, with characteristic odor.

 

Pharmacotherapeutic group:

Androgen hormone

 

Pharmacological Properties:

 

Pharmacodynamic properties

Testosterone Cypionate is a testosterone ester. Testosterone is the primary androgen hormone synthesized and released by the testes. It is responsible for the growth and development of male sexual organs and secondary sexual characteristics (maturation of the prostate, seminal vesicles, penis and scrotum), male distribution of the hair (without, pubis, chest), development of the larynx, body musculature and fat distribution. It retains nitrogen, sodium, potassium and phosphorus, increases anabolism and reduces protein catabolism. Premature increase in plasma testosterone concentration during the prepubertal period causes epiphyses to close and growth to stop. It stimulates the production of erythropoietin and erythrocytes. Through feedback mechanism it inhibits the secretion of luteinizing hormone and follicle-stimulating pituitary and causes suppression of spermatogenesis. In women it inhibits the pituitary gonotrophic function, ovarian function, mammary glands, endometrial atrophy. Due to estrogen-antagonistic action it is used in the treatment of uterine myoma, endometriosis, breast cancer. Manifest beneficial action during the climacteric period.

 

Pharmacokinetic properties

Testosterone Cypionate is absorbed slowly. The maximum plasma concentration is achieved over 72 hours after intramuscular administration. Duration of action 2 – 4 weeks. In the blood, about 98% testosterone is coupled with a specific fraction of globulin, which binds testosterone and estradiol. Biotransformation occurs in the liver up to various 17-ketosteroids, which after conjugation with glucuronic or sulfuric acid are eliminated with urine (about 90%). Approximately 6% of the absorbed preparation is removed with the feces in free form.

 

Therapeutic indications

In men – hormone replacement therapy in disorders caused by testosterone deficiency:

  • – retaining sexual maturation;
  • – eunuchoidism, undevelopment of the genital organs;
  • – male climax impotence (decreased libido and physical and intellectual activity);
  • – post-castration syndrome (androgenic deficit after castration);
  • – osteoporosis caused by androgen insufficiency.

 

Dosage and Mode of Administration

Deep intramuscular. The dose is individually determined depending on the disease, gender, age, clinical efficacy.

Usually, in adults, it is given intramuscularly 50 – 200 mg once every 2-4 weeks. The dose of 400 mg per month is not recommended. The duration of treatment is determined individually.

In hypogonadism in men like eunuchoidism the recommended doses are 50 – 400 mg every 2-4 weeks.

In case of retention of sexual maturation, it is administered 50 to 200 mg every 2-4 weeks for 4-6 months.

In breast cancer inoperable in women: 200-400 mg every 2-4 weeks.

The preparation is not given intravenously!

Pharmaceutical name:

Testosterone Cypionate

Active Life:

15-16 days

Average Dose:

Men 250-1000 mg/week

Water Retention:

Yes, high

Aromatization:

Yes, high

Steroid cycle:

bulking

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